Recurrent venous thrombosis – an unusual first presentation of autoimmune polyendocrinopathy syndrome type 3B
Recurrent venous thromboembolism (VTE) is a complex clinical problem, and there is a lack of expert consensus regarding the management of this presentation. Autoimmune conditions have long been associated with an increased risk of thrombosis via multiple mechanisms such as chronic inflammation, immune complex deposition and immunoparesis.
Artificial intelligence (AI) or augmented intelligence? How big data and AI are transforming healthcare: Challenges and opportunities
Healthcare has evolved significantly from its inception, when the sanctity of the doctor-patient relationship was based on Hippocratic traditions. William Osler described medicine as ‘a science of uncertainty and an art of probability’. The human art of healing was embedded in a relationship of trust, with history-taking and the ritual of human touch via physical examination being critical methods to reach a diagnosis and prescribe treatment.
Pancreatic cancer mortality in South Africa: A case-control study
Globally, where pancreatic cancer is defined as all types of cancers originating in the pancreas, it is the twelfth most common malignancy and the seventh leading cause of cancer death in both sexes. Worldwide, there were 458 918 new cases of pancreatic cancer and 432 242 deaths in 2018. In South Africa (SA), pancreatic cancer ranked seventh among all cancer deaths in 2020 in both sexes. Similarly, pancreatic cancer was the seventh leading cause of cancer death among males in SA in 2020, whereas it was the sixth in females.
The characteristics of dermatology inpatients seen at the quaternary Inkosi Albert Luthuli Central Hospital in Durban, South Africa, over a 5-year period – 2015 – 2020
Dermatology is an outpatient-centred specialty frequently dealing with non-acute medical conditions. However, dermatologists admit and manage patients who are severely ill and/or have complicated cutaneous diseases. The reasons for dermatology inpatient admission can range from the severity of the disease and comorbid diseases to lack of transport and psychosocial support.
Factors influencing in-hospital mortality for salvage percutaneous transjugular intrahepatic portosystemic shunting in cirrhotic patients with recalcitrant variceal bleeding after failed endoscopic intervention
Acute variceal bleeding (AVB) is the most serious acute life-threatening complication of portal hypertension, especially in patients with hepatic decompensation. Rapid and sustained control of bleeding is the immediate priority, but despite conventional treatment, including urgent fluid and blood resuscitation, vasoactive drugs, prophylactic antibiotics and endoscopic intervention, treatment fails in up to 10% of patients, who continue to bleed. In this high-risk group, further immediate options include a second attempt at endoscopic intervention and balloon or stent tamponade to temporarily control variceal bleeding.
Evaluation of the impact of PEPFAR transition on retention in care in South Africa’s Western Cape Province
Since 2003, the President’s Emergency Plan for AIDS Relief (PEPFAR) has been the USA’s most ambitious initiative to combat the global burden of HIV/AIDS and tuberculosis. PEPFAR is the largest contributor to global HIV/AIDS efforts. From 2004 to 2016, PEPFAR invested USD72.7 billion globally in HIV and TB, including contributions to the Global Fund. PEPFAR has increased the number of people receiving HIV treatment globally, and decreased HIV-related mortality by 10.5% when compared with non-PEPFAR-supported countries.
Progress towards 90-90-90 and 95-95-95 strategy implementations and HIV positivity trends in the City of Johannesburg
Globally by 2020, ~38 million people were living with HIV, and of these, 6.1 million did not know that they were HIV positive. Globally, positive progress has been made towards elimination of HIV through implementation of the 90-90-90 strategy by 2020, which later evolved to the 95-95-95 strategy, meaning that 95% of people living with HIV (PLHIV) should know their HIV status, 95% of people who know their status will be on antiretroviral medication (ARVs) and 95% of all patients receiving antiretroviral therapy (ART) will be virally suppressed by 2025.
Health Professions Council of South Africa
Attempts allowed: 2
70% pass rate
South African Medical Journal - January 2024 Vol 114 No 1